Shuo Wu, Ping Yang, Zilong Geng, Yige Li, Zhizhao Guo, Yingmei Lou, Shasha Zhang, Junhao Xiong, Huan Hu, Xiaoling Guo, William T. Pu, Yan Zhang, Dan Zhu & Bing Zhang. Base editing effectively prevents early-onset severe cardiomyopathy in Mybpc3 mutant mice. Cell Res. 09 Feb. 2024

Huan Hu, Zilong Geng, Shasha Zhang, Yuejuan Xu, Qingjie Wang, Sun Chen, Bing Zhang*, Kun Sun * and Yanan Lu*, Rare copy number variation analysis identifies disease-related variants in atrioventricular septal defect patients. 03 February 2023, DOI 10.3389/fgene.2023.1075349

Junyi Yu, Wei Wang, Jining Yang, Ye Zhang, Xue Gong, Hao Luo, Nian Cao, Zaicheng Xu, Miao Tian, Peili Yang, Qiao Mei, Zhi Chen, Zhuxin Li, Chuanwei Li, Xudong Duan, Qing Rex Lyu, Chen Gao, Bing Zhang, Yibin Wang, Gengze Wu and Chunyu Zeng. LncRNA PSR Regulates Vascular Remodeling Through Encoding a Novel Protein Arteridin. Circulation Research. 2022; 131:768-787

Xue Gong, Miao Tian, Nian Cao, Peili Yang, Zaicheng Xu, Shuo Zheng, Qiao Liao, Caiyu Chen, Cindy Zeng , Pedro A Jose , Da-Zhi Wang , Zhao Jian , Yingbin Xiao , Ding-Sheng Jiang , Xiang Wei , Bing Zhang , Yibin Wang , Ken Chen , Gengze Wu , Chunyu Zeng. Circular RNA circEsyt2 regulates vascular smooth muscle cell remodeling via splicing regulation. J Clin Invest. 2021 Dec 15;131(24):e147031. doi: 10.1172/JCI147031.

Pengyi Yan 1, Zixuan Li 1, Junhao Xiong 1, Zilong Geng 1, Weiting Wei 1, Yan Zhang 2, Gengze Wu 3, Tao Zhuang 4, Xiaoyu Tian 5, Zhijie Liu 6, Junling Liu 7, Kun Sun 1, Fengyuan Chen 1, Yuzhen Zhang 4, Chunyu Zeng 3, Yu Huang 8, Bing Zhang*. LARP7 ameliorates cellular senescence and aging by allosterically enhancing SIRT1 deacetylase activity. Cell Reports. 2021 Nov 23;37(8):110038. doi: 10.1016/j.celrep.2021.110038.

Xiaodong Liang, Shuo Wu, Zilong Geng, Li Liu, Shasha Zhang, Shiyan Wang, Yan Zhang, Yu Huang, Bing Zhang*. LARP7 Suppresses Endothelial-to-Mesenchymal Transition by Coupling with TRIM28. Circ Res. 2021 Sep 10. doi: 10.1161/CIRCRESAHA.121.319590. Online ahead of print.

Huijing Yu#; Fang Zhang#; Pengyi Yan#; Shasha Zhang#; Yingmei Lou; Zilong Geng; Zixuan Li; Yan Zhang; Yuejuan Xu; Yanan Lu; Chen Chen; Daowen Wang; Wei Zhu; Xinyang Hu; Jian’an Wang; Tao Zhuang; Yuzhen Zhang; Gengze Wu; Junling Liu; Chunyu Zeng; William T. Pu; Kun Sun; Bing Zhang*; LARP7 protects against heart failure by enhancing mitochondrial biogenesis, Circulation, 2021, 120(050812). IF>23

Fang Zhang, Pengyi Yan, Huijing Yu,  Huangying Le, Zixuan Li, Jiahuan Chen, Xiaodong Liang, Shiyan Wang, Weiting Wei, Li Liu, Yan Zhang,  Xing Ji, Anyong Xie,  Wantao Chen,  Zeguang Han,  William T. Pu,  Sun Chen,  Yingwei Chen,  Kun Sun, Baoxie Ge,  and Bing Zhang*.  LARP7 Is a BRCA1 Ubiquitinase Substrate and Regulates Genome Stability and Tumorigenesis. Cell Reports 32, 107974, July 28, 2020

Miao Y, Tian L, Martin M, Paige SL, Galdos FX, Li J, Klein A, Zhang H, Ma N, Wei Y, Stewart M, Lee S, Moonen J-R, Zhang B, Grossfeld P, Mital S, Chitayat D, Wu JC, Rabinovitch M, Nelson TJ, Nie S, Wu SM, Gu  Intrinsic Endocardial Defects Contribute to Hypoplastic Left Heart Syndrome, Cell Stem Cell, 7 August 2020

Jiahuan Chen, Xiaodong Liang, Shasha Zhang, Shiyan Wang, Sara P. Garcia, Pengyi Yan, Huijing Yu, Zixuan Li, Li Liu, Fang Zhang, Weiting Wei, Huangying Le, Yan Zhang, Guo-cheng Yuan, Sun Chen, Yingwei Chen, Kun Sun, William T. Pu  and Bing Zhang*. Two faces of bivalent domain regulate VEGFA responsiveness and angiogenesis. Cell Death & Disease. (2020) 11:75 https://doi.org/10.1038/s41419-020-2228-3

Akerberg BN, Gu F, VanDusen NJ, Zhang X, Dong R, Li K, Zhang B, Zhou B, Sethi I, Ma Q, Wasson L, Wen T, Liu J, Dong K, Conlon FL, Zhou J, Yuan GC, Zhou P, Pu WT. A reference map of murine cardiac transcription factor chromatin occupancy identifies dynamic and conserved enhancers. Nat Commun. 2019 Oct 28;10(1):4907. doi: 10.1038/s41467-019-12812-3

Shiyan Wang1†, Jiahuan Chen1†, Sara P. Garcia2†, Xiaodong Liang1†, Fang Zhang1, Pengyi Yan1, Huijing Yu1, Weiting Wei1, Zixuan Li1, Jingfang wang1, Huangying Le1, Zeguang Han1, Xusheng Luo3, Daniel S. Day4, Sean M. Stevens5, Yan Zhang6, Peter J. Park4, Zhi-jie Liu7,  Kun Sun1,  Guo-cheng Yuan2*, William T. Pu5,8*, Bing Zhang1. A dynamic and integrated epigenetic program at distal region orchestrates transcriptional responses to VEGFA. Genome Res. 2019 Feb;29(2):193-207. doi: 10.1101/gr.239053.118.

Wang C, Chen J, Zhang Q, Li W, Zhang S, Xu Y, Wang F, Zhang B, Zhang Y, Gao WQ, Elimination of CD4lowHLA-G+ T cells overcomes castration-resistance in prostate cancer therapy, Cell Res., 2018 Oct 8. doi: 10.1038/s41422-018-0089-4

1. Chen, J., Y. Fu, D.S. Day, Y. Sun, S. Wang, X. Liang, F. Gu, F. Zhang, S.M. Stevens, P. Zhou, K. Li, Y. Zhang, R.-z. Lin, L.E.H. Smith, J. Zhang, K. Sun, J.M. Melero-Martin, Z. Han, P.J. Park, B. Zhang, and W.T. Pu (2017). "VEGF amplifies transcription through ETS1 acetylation to enable angiogenesis." Nature Communications 8(1): p. 383. (IF>10)

2. Yu, W., F. Zhang, S. Wang, Y. Fu, J. Chen, X. Liang, H. Le, W. T. Pu and B. Zhang (2017). "Depletion of polycomb repressive complex 2 core component EED impairs fetal hematopoiesis." Cell Death Dis 8(4): e2744. 

1. Day, D. S., B. Zhang, S. M. Stevens, F. Ferrari, E. N. Larschan, P. J. Park and W. T. Pu (2016). "Comprehensive analysis of promoter-proximal RNA polymerase II pausing across mammalian cell types." Genome Biol 17(1): 120. co-first and co-corresponding author.

1. Zhang, Q., J. Qin, L. Zhong, L. Gong, B. Zhang, Y. Zhang and W. Q. Gao (2015). "CCL5-Mediated Th2 Immune Polarization Promotes Metastasis in Luminal Breast Cancer." Cancer Res 75(20): 4312-4321.

2. Sun, Y., C. H. Liu, J. P. SanGiovanni, L. P. Evans, K. T. Tian, B. Zhang, A. Stahl, W. T. Pu, T. M. Kamenecka, L. A. Solt and J. Chen (2015). "Nuclear receptor RORalpha regulates pathologic retinal angiogenesis by modulating SOCS3-dependent inflammation." Proc Natl Acad Sci U S A 112(33): 10401-10406. 

1. Zhang, B. and W. T. Pu (2014). "Notching up vascular regeneration." Cell Res 24(7): 777-778. 

2. Zhang, B., W. Xiao, H. Qiu, F. Zhang, H. A. Moniz, A. Jaworski, E. Condac, G. Gutierrez-Sanchez, C. Heiss, R. D. Clugston, P. Azadi, J. J. Greer, C. Bergmann, K. W. Moremen, D. Li, R. J. Linhardt, J. D. Esko and L. Wang (2014). "Heparan sulfate deficiency disrupts developmental angiogenesis and causes congenital diaphragmatic hernia." J Clin Invest 124(1): 209-221. 

1. Zhang, B. and W. T. Pu (2013). "The mysterious origins of coronary vessels." Cell Res 23(9): 1063-1064. 

2. Zhang, B., D. S. Day, J. W. Ho, L. Song, J. Cao, D. Christodoulou, J. G. Seidman, G. E. Crawford, P. J. Park and W. T. Pu (2013). "A dynamic H3K27ac signature identifies VEGFA-stimulated endothelial enhancers and requires EP300 activity." Genome Res 23(6): 917-927. 

1. He, A., Q. Ma, J. Cao, A. von Gise, P. Zhou, H. Xie, B. Zhang, M. Hsing, D. C. Christodoulou, P. Cahan, G. Q. Daley, S. W. Kong, S. H. Orkin, C. E. Seidman, J. G. Seidman and W. T. Pu (2012). "Polycomb repressive complex 2 regulates normal development of the mouse heart." Circ Res 110(3): 406-415. 

1.Zhou, B., L. B. Honor, H. He, Q. Ma, J. H. Oh, C. Butterfield, R. Z. Lin, J. M. Melero-Martin, E. Dolmatova, H. S. Duffy, A. Gise, P. Zhou, Y. W. Hu, G. Wang, B. Zhang, L. Wang, J. L. Hall, M. A. Moses, F. X. McGowan and W. T. Pu (2011). "Adult mouse epicardium modulates myocardial injury by secreting paracrine factors." J Clin Invest 121(5): 1894-1904. 

1.Zhang, B., U. M. Dietrich, J. G. Geng, R. Bicknell, J. D. Esko and L. Wang (2009). "Repulsive axon guidance molecule Slit3 is a novel angiogenic factor." Blood 114(19): 4300-4309.

1. Gong, L., B. Zhang, Y. Zhang, H. Hu, Z. Zhao and X. Liu (2007). "Cloning, expression and purification of human S-adenosylmethionine decarboxylase gene alpha subunit." Chin J Physiol 50(1): 29-33.

2. Tian, H., X. Liu, B. Zhang, Q. Sun and D. Sun (2007). "Adenovirus-mediated expression of both antisense ornithine decarboxylase and S-adenosylmethionine decarboxylase inhibits lung cancer cell growth." Acta Biochim Biophys Sin (Shanghai) 39(6): 423-430.

1. Gong, L., C. Jiang, B. Zhang, H. Hu, W. Wang and X. Liu (2006). "Adenovirus-mediated expression of both antisense ornithine decarboxylase and s-adenosylmethionine decarboxylase induces G1 arrest in HT-29 cells." J Biochem Mol Biol 39(6): 730-736.

2. Zhang, B., X. X. Liu, Y. Zhang, C. Y. Jiang, Q. S. Teng, H. Y. Hu, W. Wang and L. Gong (2006). "Adenovirus-mediated expression of both antisense ODC and AdoMetDC inhibited colorectal cancer cell growth in vitro." Acta Pharmacol Sin 27(3): 353-359.

3. Zhang, B., X. X. Liu, Y. Zhang, C. Y. Jiang, H. Y. Hu, L. Gong, M. Liu and Q. S. Teng (2006). "Polyamine depletion by ODC-AdoMetDC antisense adenovirus impairs human colorectal cancer growth and invasion in vitro and in vivo." J Gene Med 8(8): 980-989.

1. Zhang, Y., X. X. Liu, B. Zhang, H. Y. Hu and L. Gong (2005). "Antitumor effect of antisense ODC adenovirus on human prostate cancer cells." Prostate Cancer Prostatic Dis 8(3): 280-286.

2. Hu, H. Y., X. X. Liu, C. Y. Jiang, Y. Lu, S. L. Liu, J. F. Bian, X. M. Wang, Z. Geng, Y. Zhang and B. Zhang (2005). "Ornithine decarboxylase gene is overexpressed in colorectal carcinoma." World J Gastroenterol 11(15): 2244-2248.